More research is coming out about an issue in many children with Autism which deals with cerebral folate deficiency. Cerebral folate deficiency can cause issues with speech, cognition, awareness, focus, etc. and is something that can be treated.
Today I want to discuss folate, folinic acid, and some new research that is recently being released on cerebral folate deficiency in Autism. Cerebral folate deficiency has been known about in the medical community for a number of years. Children often have poor growth, speech problems, nervous system problems, attention issues, comprehension problems, and many times, at an early age, their heads stop growing normally. And when testing is done on children with these issues, what is called antibody testing, they discover these immune folate reactions that are happening to the folate transport receptors.
When we talk about folate uptake, and many times people think of folic acid, but to be effectively utilized by the brain for growth and development it must be transported through the blood, in the cerebral spinal fluid and then into the brain tissue. If there are antibodies that block those receptors then we have an issue where blood folate levels rise but the cerebral spinal fluid levels drop and then the issues with folate deficiency happen.


